Doxorubicin is an anticancer medication that is used to treat several cancers such as ovarian cancer, multiple myeloma, and Kaposi cancer. The brand name of this medication is Pegdoxine and it is manufactured by Arechar Healthcare. It is a chemotherapy medicine that belongs to anthracycline. This injection possesses antineoplastic properties and it slows the growth of the cancer cells. The Pegylated liposomal doxorubicin hydrochloride injection functions by inhibiting the synthesis of DNA and RNA by intercalating with the base pairs. In addition to this, it can also cause the steric obstruction of topoisomerase II which is needed for DNA synthesis. A complex is formed when the medication binds to iron and this complex can bind to the DNA and produce free radicals. Free radicals can furthermore cleave the cell membranes and genetic material. This injection is a pegylated formulation and it protects the liposomes and therefore increases the circulation time. The injection is available as a 20mg formulation and is taken intravenously.
Some of the precautions to remember when taking Doxorubicin Injection are –
· Some of the components of the doxorubicin injection can cause an allergic reaction in a few patients. Hence, it is advisable to gather complete information before starting the use.
· Inform the doctor about all the medication and supplements you take since they can interfere with the absorption of doxorubicin. Some of the medications to avoid are – cytarabine, phenobarbital, dexrazoxane, etc.
· The injection can interfere with the menstrual cycle in females. Hence it is advisable to avoid pregnancy since Doxorubicin can harm the fetus.
Some of the side effects of Doxorubicin are such as –
· Vomiting
· Nausea
· Hair loss
· Dizziness
· Stomach pain
· Eye pain
· Red discoloration in urine
· Weight gain
· Sores in the mouth and throat
· Tingling in the hands and feet
The price of Doxorubicin hydrochloride 20mg can provide these medications injection is high therefore it is advisable to refer to Magicine Pharma as they can provide them at a low price.
FAQ (Frequently Asked Questions)
Q1 - Where to store Pegdoxine?
Ans - It is advisable to store the Pegdoxine at a place of 2° - 8°C.
Q2 - Can I drink alcohol with Doxorubicin?
Ans - Avoid drinking alcohol during the treatment with Doxorubicin even though no interactions of both are known.
Q3 - How long is the treatment with Doxorubicin?
Ans - The doctor decides for how long the treatment with Doxorubicin injection will continue depending on the condition, stage, and health of the patient.
Comments