Pazopanib is used in the treatment of advanced renal cell carcinoma (kidney cancer).Pazopanib also known by the brand name Paznib is manufactured by Arechar Healthcare. It is a multi-tyrosine kinase inhibitor as it blocks the formation of proteins that form blood vessels in cancer cells. Hence, it is called an anti-angiogenesis treatment as the cancer cells do not form the blood vessels needed for the growth of tumors. Pazopanib 200mg tablets are given orally and are advisable to take this medication 1 hour before or 2 hours after food.
Creatinine Clearance - Creatinine is the waste product formed from muscle tissue breakdown. Usually, it is excreted from the body via urine. The rate of filtration by the kidney is called GFR (glomerular filtration rate) and is 90ml/min or more in healthy patients. GFR cannot be measured itself hence, the creatinine test is used for it. The doctors use the kidney’s ability to excrete creatinine as a way to measure how well they are working. Risks of kidney disease arise after the GFR is below 60ml/min.The use of Pazopanib in patients with creatinine clearance less than 30ml/min is advised to be cautious.
Side Effects of Pazopanib Tablets Are Such As –
· Allergies – skin rashes, itching, and swelling of the face. Secondly, blisters redness, and peeling of the skin of the palm and sole may be observed.
· Liver complications – pain in the right side of the body, yellowing of skin, eyes, and urine a common signs of possible liver infection
· Breathing problems – shortness of breath, dizziness and weakness
· Severe headaches, decreased vision, and loss of balance
· Stomach problems – stomach pain, nausea, constipation, bloody or black stool, vomiting, and loss of appetite
· Irregular blood pressure, chest pain, irregular heartbeat, and seizures.
· Some common side effects are – weight loss, change in taste, skin discoloration, and hair color changes.
Precautions to Remember When Taking Pazopanib Are Such As -
· Do not take this medicine with food, especially grapefruit and its juice.
· This drug interacts with other medications like cisapride, fluconazole, thioridazine and pimozide.
· Avoid this medication if there are any allergies to the ingredients. Therefore, it is always better to check the ingredients and consult a physician.
· Pazopanib can cause serious liver damage hence, informing the doctors in case of any prior liver conditions and the appearance of any liver complication signs is highly advisable.
· Pause the treatment till 2 weeks after the surgery as this drug may reduce the healing of the surgical site.
Conclusion
The price of Pazopanib 200mg is high therefore you can purchase it from Magicine Pharma at an affordable price. Magicine Pharma provides Pazopanib for a discount of up to 15%.
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