Multiple myeloma is a cancer which starts in the white blood cells.it is also called as the Kahler’s disease and there is no set cure for this cancer as of now. The plasma cells form the antibodies however in the multiple myeloma these cells undergo uncontrollable growth and release excess of the immunoglobulin in the bloodstream which damages the organs. The plasma cells also triggers the cells to corrode the bones. Some of the signs of getting multiple myeloma are such as –
Bone pain
Infections
Severe thirst
Weakness
Weight loss
Constipation
Numbness in the legs and arms
Loss of appetite
Denosumab or also known by the brand name Prolia is an anticancer medication which is used for the treatment of multiple myeloma as it decreases the resorption of the bones. Denosumab is a RANK ligand inhibitor and it is an igG2 monoclonal antibody. RANK ligand is the first signal which initiates the removal or resorption of the bones. This medication stops the RANK ligand from activating the receptor. The inhibition of RANK stops the oseteoclast (cells that destroy the bones) formation and functioning.
Some precautions to follow when using Denosumab 60mg Injection –
Inform the doctor beforehand if you are allergic to any of the component of the Denosumab. The allergic reaction can lead to redness, swelling and itching on the injection. Hence, it is advisable to find an alternative medication for the loss of bones.
The Denosumab injection can interact with other supplements, prescription and non-prescription medications. Denosumab can interact with anti-angiogenic medications such as – Sorafenib, Sunitinib, Everolimus, and Zoledronic acid.
Inform the doctor about low level of calcium before starting the treatment.
Tell the doctor about anemia, infection in the mouth, gums and teeth and also any disease in regards to the blood.
Inform the doctor in case of pregnancy or breast feeding as the denosumab injection can harm the fetus.
The Denosumab injection can cause osteonecrosis of the jaw.
The side effects of Denosumab are such as –
Blisters on the skin
Headache
Stomach pain
Nausea
Diarrhea
Muscle pain
Swelling of arms and legs
Fever
Chills
Ear pain
Painful urination
The Denosumab Injection price is quite high therefore it’s advisable to buy this medication using Magicine Pharma as they provide various discounts and offers and provide this injection at a lower rate.
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